BMP-4

• Target:

  COX|||Interleukin|||IFNAR

• Related Pathways:

  Neuroscience|||Immunology/Inflammation

• Bioactivity:

  BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.

• Smiles:

  C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@@H] (CC1=CN=CN1) C (O) =O) =O) CCCNC (=N) N) =O) CCCNC (=N) N) =O) CS) =O) CC (N) =O) (=O) [C@H]2N (C ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CCCNC (=N) N) N) =O) CCCCN) =O) CCCCN) =O) CC (N) =O) =O) CCC2

• Molecular Formula:

  C52H93N25O13S

• Molecular Weight:

  1308.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1629625-47-3