BMP-22

CAT: 0931-T36138-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T36138-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1306684-90-1

Target

Others, PDE

Related Pathways

Metabolism, Others

Bioactivity

BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM) . It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 (0.1-1,000 nM) inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine in vitro in a concentration-dependent manner. It inhibits LPC-dependent MM1 cell invasion of a human umbilical vein endothelial cell (HUVEC) monolayer. BMP-22 (0.5 mg/kg per day) decreases the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis.

Smiles

C(CCCCCCCCCCCCCC)C1=CC=C(CP(=O)(O)O)C=C1

Molecular Formula

C22H39O3P

Molecular Weight

382.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
574213	BMP-22
167765-01	BMP-2, Recombinant, Human (human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP) discontinued
167769-01	BMP-7, Recombinant, Human, aa1-139 (human BMP-7, BMP-7, BMP7, BMP 7, h-BMP-7, rh-BMP-7, recombinant human BMP-7, recombinant BMP-7, BMP) discontinued
167763-01	BMP-13, Recombinant, Human, aa1-120 (Human BMP-13, BMP-13, BMP13, BMP 13, h-BMP-13, rh-BMP-13, recombinant human BMP-13, recombinant BMP-13, BMP) discontinued
167766-01	BMP-4, Recombinant, Human, aa1-116 (human BMP-4, BMP-4, BMP4, BMP 4, h-BMP-4, rh-BMP-4, recombinant human BMP-4, recombinant BMP-4, BMP) discontinued
208604-01	BMP-2 (BMP-2A) (Biotin)
ant-312	BMP-7
GWB-CC86ED	BMP-2
520615-01	BMP-8
308016-01	BMP-6

BMP-22

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