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Butyrolactone Ia

CAT: 0931-TN8943-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN8943-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
942986-92-7
Target
NO Synthase, Interleukin, Autophagy
Related Pathways
Immunology/Inflammation, Autophagy
Bioactivity
Butyrolactone Ia is an inhibitor of NO production, with an IC50 of 18 μM. It suppresses the mRNA expression of iNOS and inflammatory cytokine IL-1β induced by LPS. Additionally, Butyrolactone Ia regulates autophagy (autophagy) in HeLa cells and exhibits immunosuppressive activity.
Smiles
C([C@]1(C(O)=O)C(=C(O)C(=O)O1)C2=CC=C(O)C=C2)C3=CC(CC=C(C)C)=C(O)C=C3
Molecular Formula
C23H22O7
Molecular Weight
410.417
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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