Escin IA

• Target :

  HIV Protease

• Related Pathways :

  Microbiology/Virology|||Proteases/Proteasome

• Purity :

  0.9981

• Bioactivity :

  Escin IA (Escin IA; Aescin IA) is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 ?M. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression[1][2].

• Smiles :

  [H][C@@]1(O[C@H]2[C@H](O)[C@@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@]([H])(O[C@H]3CC[C@@]4(C)[C@@]([H])(CC[C@]5(C)[C@]4([H])CC=C4[C@]6([H])CC(C)(C)[C@@H](OC(=O)C(\C)=C\C)[C@H](OC(C)=O)[C@]6(CO)[C@H](O)C[C@@]54C)[C@@]3(C)CO)O[C@@H]2C(O)=O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

• Molecular Formula :

  C55H86O24

• Molecular Weight :

  1131.26

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  123748-68-5