Escin IA

• Target:

  HIV Protease

• Related Pathways:

  Microbiology/Virology|||Proteases/Proteasome

• Purity:

  0.9981

• Bioactivity:

  Escin IA (Escin IA; Aescin IA) is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 ?M. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression[1][2].

• Smiles:

  [H][C@@]1 (O[C@H]2[C@H] (O) [C@@H] (O[C@]3 ([H]) O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]3O) [C@] ([H]) (O[C@H]3CC[C@@]4 (C) [C@@] ([H]) (CC[C@]5 (C) [C@]4 ([H]) CC=C4[C@]6 ([H]) CC (C) (C) [C@@H] (OC (=O) C (\C) =C\C) [C@H] (OC (C) =O) [C@]6 (CO) [C@H] (O) C[C@@]54C) [C@@]3 (C) CO) O[C@@H]2C (O) =O) O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]1O

• Molecular Formula:

  C55H86O24

• Molecular Weight:

  1131.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  123748-68-5