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Cimicifugic acid D

CAT: 0931-TN11489-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN11489-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
219986-51-3
Target
Calcium Channel
Related Pathways
Membrane transporter/Ion channel, Metabolism
Bioactivity
Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyl tartaric acid ester that can induce vasorelaxation and an endothelium-dependent relaxation mechanism in pre-constricted rat aortic strips. During norepinephrine-induced contractions in rat aortic strips, Cimicifugic acid D inhibits extracellular Ca2+ influx through receptor-operated Ca2+ channels (ROC), while it does not affect voltage-dependent Ca2+ channels (VDC) or K+-induced contractions.
Smiles
[C@@H]([C@](CC1=CC=C(O)C=C1)(C(O)=O)O)(OC(/C=C/C2=CC(O)=C(O)C=C2)=O)C(O)=O
Molecular Formula
C20H18O10
Molecular Weight
418.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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