7a-Hydroxyfrullanolide

CAT: 0931-TN10130-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TN10130-01Size:10 mg
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CAS Number
105578-87-8
Target
Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Bioactivity
7a-Hydroxyfrullanolide possesses anticancer properties and can reduce the polymerization of ?- and ?-tubulins. It preferentially binds to ?-tubulin over ?-tubulin. Additionally, 7a-Hydroxyfrullanolide induces a DNA damage response, causing cell arrest in the G2/M phase. This compound is a eucalyptolide sesquiterpene lactone (SL) and can be extracted from Asteraceae family flowering plants.
Smiles
O[C@]12[C@](C=3[C@@](C)(CC1)CCCC3C)(OC(=O)C2=C)[H]
Molecular Formula
C15H20O3
Molecular Weight
248.318
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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