Nintedanib-d8

• Target :

  VEGFR|||FGFR|||PDGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity :

  Nintedanib-d8 is a deuterated compound of Nintedanib. Nintedanib has a CAS number of 656247-17-5. Nintedanib is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3, FGFR1-4, and PDGFR?/?, respectively) .

• Smiles :

  N1C2=C(C=CC(C(OC)=O)=C2)/C(=C(/NC2=CC=C(N(C)C(=O)CN3C([2H])([2H])C([2H])([2H])N(C)C([2H])([2H])C3([2H])[2H])C=C2)\C2=CC=CC=C2)/C1=O

• Molecular Formula :

  C31H25D8N5O4

• Molecular Weight :

  547.67

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1624587-87-6