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Nintedanib-d8

CAT: 0931-TMIJ-0333-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TMIJ-0333-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1624587-87-6
Target
VEGFR, FGFR, PDGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
Nintedanib-d8 is a deuterated compound of Nintedanib. Nintedanib has a CAS number of 656247-17-5. Nintedanib is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3, FGFR1-4, and PDGFRα/β, respectively) .
Smiles
N1C2=C(C=CC(C(OC)=O)=C2)/C(=C(/NC2=CC=C(N(C)C(=O)CN3C([2H])([2H])C([2H])([2H])N(C)C([2H])([2H])C3([2H])[2H])C=C2)\C2=CC=CC=C2)/C1=O
Molecular Formula
C31H25D8N5O4
Molecular Weight
547.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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