Products for Research Use Only
RegisterLogin

Nintedanib-13C-d3

CAT: 0931-TMIH-0393-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TMIH-0393-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1624587-84-3
Target
PDGFR, FGFR, VEGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
Nintedanib-13C-d3 is the 13C and deuterated compound of Nintedanib. Nintedanib has a CAS number of 656247-17-5. Nintedanib is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3, FGFR1-4, and PDGFRα/β, respectively) .
Smiles
[2H]C([2H])([2H])N1CCN(CC(=O)N(C)C2=CC=C(N\C(C3=CC=CC=C3)=C3/C(=O)NC4=CC(=CC=C34)C(=O)OC)C=C2)CC1
Molecular Formula
C31H30D3N5O4
Molecular Weight
542.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Intedanib-d3
CAS Number1624587-84-3
PubChem CID136242406
IUPAC Namemethyl 2-hydroxy-3-[N-[4-[methyl-[2-[4-(trideuteriomethyl)piperazin-1-yl]acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
Molecular FormulaC31H33N5O4
Molecular Weight542.6
XLogP4.3
Topological Polar Surface Area101
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Heavy Atom Count40
Formal Charge0
Complexity892
SMILES
[2H]C([2H])([2H])N1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
InChI
InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,33,38H,15-18,20H2,1-3H3/i1D3
InChIKey
CPMDPSXJELVGJG-FIBGUPNXSA-N
Chemical Structure
2D Structure
2D structure of Intedanib-d3
CAS: 1624587-84-3
CID: 136242406
Formula: C31H33N5O4
MW: 542.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight542.6
XLogP34.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Exact Mass542.27208479
Monoisotopic Mass542.27208479
Topological Polar Surface Area101 Ų
Heavy Atom Count40
Formal Charge0
Complexity892
Isotope Atom Count3
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
TMIJ-0148-01Avanafil-13C-d3
TMIJ-0111-01Azithromycin-13C-d3
TMIJ-0066-01Alosetron-13C-d3
TMIH-0550-01Taltirelin-13C-d3
TMIH-0092-01Apalutamide-13C-d3
TMID-0209-01Tadalafil-13C-d3
TMIJ-0186-01Bromocriptine-13C-d3
TMIJ-0185-01Telmisartan-13C-d3
TMIJ-0124-01Regorafenib-13C-d3
TMIJ-0110-01Clarithromycin-13C-d3

Alternative Products

CatalogName
JH912687Nintedanib-[13C, d3]
HY-50904S1Nintedanib-13C, d3
RM-N140509-01Nintedanib-13C-d3
AR-N01607-01Nintedanib-13C-d3 (Intedanib-13C-d3)
AR-N08784-01Nintedanib Impurity 6-13C-d3
AR-N01608-01Nintedanib-O-Methyl-13C-d3 (Intedanib-O-Methyl-13C-d3)
AR-N08730-01Nintedanib-13C-d3 Demethyl-O-Glucuronide
HY-50904SNintedanib-d3
ZPC58784-01Nintedanib d3
AR-Y01012-01YM155-13C-d3 (Sepantronium-13C-d3 Bromide)

Popular Products