Sulindac-d3

• Bioactivity :

  Sulindac-d3 is a deuterated compound of Sulindac. Sulindac has a CAS number of 38194-50-2. Sulindac is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cyclic guanosine monophosphate-phosphodiesterase (cGMP-PDE), an enzyme that inhibits the normal apoptosis signal pathway; this inhibition permits the apoptotic signal pathway to proceed unopposed, resulting in apoptotic cell death.

• Smiles :

  C1C=C2/C(=C\C3C=CC(S(=O)C([2H])([2H])[2H])=CC=3)/C(C)=C(CC(O)=O)C2=CC=1F

• Molecular Formula :

  C20H14D3FO3S

• Molecular Weight :

  359.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C