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Clozapine-d8

CAT: 0931-TMIH-0166Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TMIH-0166Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1185053-50-2
Target
5-HT Receptor, Dopamine Receptor, AChR, Adrenergic Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
Clozapine-d8 is the deuterium-labeled analog of the antipsychotic compound Clozapine, wherein eight hydrogen atoms have been replaced with the stable isotope deuterium. Like its parent molecule, Clozapine-d8 acts as a selective ligand for the D4-dopamine receptor and the 5HT2 serotonin receptor, making it a valuable internal standard for the quantitative mass spectrometric analysis of Clozapine, which is an atypical antipsychotic used primarily for the research of treatment-resistant schizophrenia and exhibits high affinity for a diverse number of neuroreceptors beyond its primary targets.
Smiles
CN1C(C(N(C=2C=3C(NC=4C(N2)=CC(Cl)=CC4)=CC=CC3)C(C1([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H]
Molecular Formula
C18H19ClN4
Molecular Weight
334.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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