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Clozapine N-Oxide

CAT: 0931-T4494-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T4494-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
34233-69-7
Target
Drug Metabolite, AChR, Dopamine Receptor, 5-HT Receptor
Related Pathways
Neuroscience, Metabolism, GPCR/G Protein
Purity
0.9994
Bioactivity
Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopamine antagonist and selective muscarinic M4 receptor agonist.
Smiles
CN1(=O)CCN(C=2C=3C(NC=4C(N2)=CC(Cl)=CC4)=CC=CC3)CC1
Molecular Formula
C18H19ClN4O
Molecular Weight
342.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
M18447-01CLOZAPINE N-OXIDE

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