Clozapine

• Target:

  AChR|||5-HT Receptor|||Dopamine Receptor|||Adrenergic Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Purity:

  0.9995

• Bioactivity:

  Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity.

• Smiles:

  CN1CCN(CC1)C1=NC2=C(NC3=C1C=CC=C3)C=CC(Cl)=C2

• Molecular Formula:

  C18H19ClN4

• Molecular Weight:

  326.82

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  5786-21-0