Valproic Acid-d15

• Target:

  Endogenous Metabolite|||Autophagy|||Mitophagy|||Gamma-secretase|||HIV Protease|||HDAC

• Related Pathways:

  Chromatin/Epigenetic|||Metabolism|||Proteases/Proteasome|||Autophagy|||Microbiology/Virology|||DNA Damage/DNA Repair|||Stem Cells|||Neuroscience

• Bioactivity:

  Valproic Acid-d15 is a deuterated compound of Valproic Acid. Valproic Acid has a CAS number of 99-66-1. Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs) in vitro. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A (sc-3511) in the inhibition of histone deacetylase.

• Smiles:

  C (C (C (C ([2H]) ([2H]) [2H]) ([2H]) [2H]) ([2H]) [2H]) (C (C (C ([2H]) ([2H]) [2H]) ([2H]) [2H]) ([2H]) [2H]) (C (O) =O) [2H]

• Molecular Formula:

  C8H1D15O2

• Molecular Weight:

  159.3

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  362049-65-8