Valproic Acid-d4

CAT: 0931-TMIJ-0163-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TMIJ-0163-01Size:1 mg
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CAS Number
87745-17-3
Target
Mitophagy|||Autophagy|||Gamma-secretase|||HIV Protease|||Endogenous Metabolite|||HDAC
Related Pathways
DNA Damage/DNA Repair|||Neuroscience|||Proteases/Proteasome|||Metabolism|||Microbiology/Virology|||Autophagy|||Chromatin/Epigenetic|||Stem Cells
Bioactivity
Valproic Acid-d4 is a deuterated compound of Valproic Acid. Valproic Acid has a CAS number of 99-66-1. Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs) in vitro. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A (sc-3511) in the inhibition of histone deacetylase.
Smiles
C(O)(=O)C(C([2H])([2H])CC)C([2H])([2H])CC
Molecular Formula
C8H12D4O2
Molecular Weight
148.24
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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