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SHR-A1201

CAT: 0931-T9901A-238-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-238-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR, Antibody-Drug Conjugates (ADCs)
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Antibody-drug Conjugate/ADC Related, JAK/STAT signaling
Bioactivity
SHR-A1201 is an antibody-drug conjugate (ADC) targeting HER2. This compound is composed of a humanized anti-HER2 antibody, the linker SMCC, and the cytotoxic payload Mertansine, which is a microtubule inhibitor. SHR-A1201 is utilized in research for HER2-positive breast cancer.
Smiles
[C@@H](OC(=O)[C@H]1N(C(C(C(CC)(C)C)=O)=O)CCCC1)(CCC2=CC(OC)=C(OC)C=C2)C3=CC(NC(CCOCCOCCNC(CCNC(=O)C4=CC(NC(CCl)=O)=CC(C(F)(F)F)=C4)=O)=O)=CC=C3
Molecular Formula
C50H63ClF3N5O12
Molecular Weight
1018.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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