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EP300/CBP ligand 2

CAT: 0931-T89972-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89972-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Epigenetic Reader Domain, Ligands for Target Protein for PROTAC
Related Pathways
Chromatin/Epigenetic, PROTAC
Bioactivity
EP300/CBP ligand 2 (compound S19) serves as a specific ligand for the bromodomain of CREB binding protein (CBP) and E1A-associated protein (EP300) . It plays a critical role in PROTAC technology by acting as a target protein ligand. By linking to an E3 ubiquitin ligase ligand via the PROTAC Linker, it facilitates the synthesis of PROTAC molecules capable of targeted protein degradation. For instance, when EP300/CBP ligand 2 is connected to the conjugate (E3 ubiquitin enzyme ligand + Linker) Thalidomide-NH-C10-Boc, it results in the formation of the PROTAC molecule dCE-2.
Molecular Formula
C20H18N6O
Molecular Weight
358.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-161960EP300/CBP ligand 2
HY-161959EP300/CBP ligand 1
MBS5785652-01CBP/p300 ligand 2
GTR19234055-01CBP/p300 ligand 3
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MBS5800438Thalidomide-NH-CBP/p300 ligand 2
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