LY 379196

• Target :

  PKC

• Related Pathways :

  Chromatin/Epigenetic|||Cytoskeletal Signaling

• Bioactivity :

  LY 379196, a potent PKC-? inhibitor (IC 50: 50 nM for PKC ?I and 30 nM for PKC ?II), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.

• Molecular Formula :

  C30H34N4O5S

• Molecular Weight :

  562.68

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C