MMAF intermediate 2

• Target :

  ADC Cytotoxin

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  MMAFintermediate 2 serves as a precursor in the synthesis of MMAF (Monomethylauristatin F) . MMAF is a potent inhibitor of tubulin polymerization and a cytotoxic component of classical antibody-drug conjugates (ADCs), including Vorsetuzumab mafodotin and SGN-CD19A, serving as the ADC Cytotoxin.

• Smiles :

  [C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC)=O)=O)C)(OC)[C@@]2(CCCN2)[H].Cl

• Molecular Formula :

  C19H29ClN2O4

• Molecular Weight :

  384.9

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  864238-20-0