MMAF intermediate 2

• Target:

  ADC Cytotoxin

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  MMAFintermediate 2 serves as a precursor in the synthesis of MMAF (Monomethylauristatin F) . MMAF is a potent inhibitor of tubulin polymerization and a cytotoxic component of classical antibody-drug conjugates (ADCs), including Vorsetuzumab mafodotin and SGN-CD19A, serving as the ADC Cytotoxin.

• Smiles:

  [C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC)=O)=O)C)(OC)[C@@]2(CCCN2)[H].Cl

• Molecular Formula:

  C19H29ClN2O4

• Molecular Weight:

  384.9

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  864238-20-0