MMAF intermediate 1

CAT: 0931-T89657-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T89657-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
161485-82-1
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
MMAFintermediate 1 serves as a precursor in the synthesis of MMAF (Monomethylauristatin F), an effective inhibitor of tubulin polymerization. MMAF is a cytotoxic component commonly used in antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. This compound plays a crucial role in the production of classic ADC cytotoxins.
Smiles
[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC)=O)=O)C)(OC)[C@]2(N(C(OC(C)(C)C)=O)CCC2)[H]
Molecular Formula
C24H36N2O6
Molecular Weight
448.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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