Products for Research Use Only

Dxd-d5

CAT: 0931-T89642-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89642-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Dxd-d5, a deuterated derivative of Dxd, acts as a potent DNAtopoisomerase I inhibitor with an IC50 value of 0.31 μM. It serves as the effective payload for the antibody-drug conjugate (ADC) targeting HER2, known as DS-8201a.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C