Dxd-d5

• Target:

  ADC Cytotoxin

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  Dxd-d5, a deuterated derivative of Dxd, acts as a potent DNAtopoisomerase I inhibitor with an IC50 value of 0.31 ?M. It serves as the effective payload for the antibody-drug conjugate (ADC) targeting HER2, known as DS-8201a.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C