Dxd

• Target :

  ADC Cytotoxin|||Topoisomerase

• Related Pathways :

  DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

• Purity :

  >99.99%

• Bioactivity :

  Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 ?M) . Dxd was used as a conjugate drug for HER2-targeted ADCs.

• Smiles :

  CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)CO)c(c3Cn1c2=O)c45

• Molecular Formula :

  C26H24FN3O6

• Molecular Weight :

  493.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1599440-33-1