Dxd

• Target:

  ADC Cytotoxin|||Topoisomerase

• Related Pathways:

  DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

• Purity:

  >99.99%

• Bioactivity:

  Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 ?M) . Dxd was used as a conjugate drug for HER2-targeted ADCs.

• Smiles:

  CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)CO)c(c3Cn1c2=O)c45

• Molecular Formula:

  C26H24FN3O6

• Molecular Weight:

  493.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1599440-33-1