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UNC8732

CAT: 0931-T89493-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89493-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2929304-05-0
Bioactivity
UNC8732 is a Targeted Protein Degradation (TPD) agent. It acts by catalyzing the production of aldehyde metabolites through amine oxidase, which subsequently binds to the C326 of the ubiquitin E3 ligase FBXO22, recruiting the SCFFBXO22 Cullin complex. This recruitment leads to the further degradation of the histone methyltransferase and the oncogene NSD2.
Smiles
O=C(NC1=CC=C2C(=C1)CCN(C(=O)CCCCCN)C2)C3=CC=C(C=C3)CN(C(=O)C4=CC=C5NC(=O)COC5=C4)C6CC6
Molecular Formula
C35H39N5O5
Molecular Weight
609.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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