Products for Research Use Only

UNC8732

CAT: 0013-GTR19237850-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237850-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UNC8732 is a targeted protein degrader that functions via aldehyde metabolite formation, enabling recruitment of the SCFFBXO22 E3 ligase complex to ubiquitinate and degrade the oncogenic histone methyltransferase NSD2. This molecule serves as a chemical probe for studying NSD2 biology and targeted protein degradation mechanisms in both cellular and in vivo cancer models.
CAS Number
2929304-05-0
Smiles
O=C (NC1=CC=C2C (=C1) CCN (C (=O) CCCCCN) C2) C3=CC=C (C=C3) CN (C (=O) C4=CC=C5NC (=O) COC5=C4) C6CC6
Molecular Formula
C35H39N5O5
Molecular Weight
609.72
Storage Conditions
-20°C
Notes
For research use only.

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