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SMARCA2/4-ligand-5

CAT: 0804-HY-172446Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172446Size:1 Each
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Description
SMARCA2/4-ligand-5 is a SMARCA2/4 ligand for PROTAC SMARCA2/4 degrader-37 (Example 4) . PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM[1].
CAS Number
2271348-89-9
UNSPSC
12352005
Target
Epigenetic Reader Domain; Ligands for Target Protein for PROTAC
Related Pathways
Epigenetics; PROTAC
Field of Research
Others
Smiles
O=C(NC1=CC(C#CC2=CC=CC(C(O)=O)=C2)=NC=C1)NC3=CC(Cl)=NC=C3
Molecular Formula
C20H13ClN4O3
Molecular Weight
392.80
References & Citations
[1]Deyao LI, et al. Preparation of bifunctional PROTAC compounds, compositions, and methods for degradation of targeted SMARCA2, SMARCA4 or BRM proteins. Patent WO2021163302 A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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