LL-K12-18

• Target:

  Molecular Glues|||CDK

• Related Pathways:

  PROTAC|||Cell Cycle/Checkpoint

• Purity:

  0.9977

• Bioactivity:

  LL-K12-18 is a dual-site molecular gel that enhances protein-protein interactions (PPIs) between CDK12-DDB1 complexes thereby promoting the degradation of Cyclin K. It potently inhibits tumor cell gene transcription and anti-proliferation.

• Smiles:

  CCN1C2=NC (N3CCN (C (CN (CC) CC) =O) CC3) =NC (NCC4=NC5=CC (Cl) =C (Cl) C=C5N4) =C2N=C1

• Molecular Formula:

  C25H32Cl2N10O

• Molecular Weight:

  559.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C