EPZ-4777

• Bioactivity:

  EPZ-4777 acts as a selective DOT1L inhibitor, effectively blocking the expression of leukemia-inducing genes by inhibiting methylation of H3K79 in cancer cells, and selectively targets and eradicates cells carrying translocations of this gene. It is utilized in tumor research.

• Smiles:

  O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (CN (CCCNC (NC4=CC=C (C (C) (C) C) C=C4) =O) C (C) C) [C@H]1O

• Molecular Formula:

  C27H40N8O4

• Molecular Weight:

  540.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1381761-52-9