EPZ-4777

• Bioactivity:

  EPZ-4777 acts as a selective DOT1L inhibitor, effectively blocking the expression of leukemia-inducing genes by inhibiting methylation of H3K79 in cancer cells, and selectively targets and eradicates cells carrying translocations of this gene. It is utilized in tumor research.

• Smiles:

  O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CN(CCCNC(NC4=CC=C(C(C)(C)C)C=C4)=O)C(C)C)[C@H]1O

• Molecular Formula:

  C27H40N8O4

• Molecular Weight:

  540.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1381761-52-9