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Lamivudine triphosphate

CAT: 0931-T88996-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88996-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
143188-53-8
Bioactivity
Lamivudine triphosphate (3TCTP), a phosphorylated form of the nucleoside analogue Lamivudine, inhibits the reverse transcriptase of HIV or HBV, blocking viral replication through chain termination. It also acts as an inhibitor of the RdRp activity of the HCVNS5B subunit. Additionally, Lamivudine triphosphate can be incorporated into nascent RNA by SARS-CoV-2 RdRp, thereby preventing mutations in the newly synthesized SARS-CoV-2 RNA.
Smiles
O=C1N(C=CC(N)=N1)[C@H]2O[C@@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)SC2
Molecular Formula
C8H14N3O12P3S
Molecular Weight
469.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C