Formycin triphosphate

• Target :

  Guanylate cyclase

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  Formycin triphosphate is a fluorescent analog of ATP, exhibiting enhanced fluorescence when binding to enzyme active sites. It acts as a competitive inhibitor of avian liver pyruvate carboxylase (pyruvate carboxylase) . Additionally, formycin triphosphate increases atrial natriuretic factor (ANF) -stimulated guanylate cyclase activity with an EC50 of approximately 90 ?M and inhibits ATP-stimulated guanylate cyclase activity with an IC50 of around 100 ?M.

• Smiles :

  O[C@H]1[C@H](C=2C=3C(NN2)=C(N)N=CN3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O

• Molecular Formula :

  C10H16N5O13P3

• Molecular Weight :

  507.18

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  16409-13-5