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Formycin triphosphate

CAT: 0931-T210016-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T210016-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
16409-13-5
Target
Guanylate cyclase
Related Pathways
GPCR/G Protein
Bioactivity
Formycin triphosphate is a fluorescent analog of ATP, exhibiting enhanced fluorescence when binding to enzyme active sites. It acts as a competitive inhibitor of avian liver pyruvate carboxylase (pyruvate carboxylase) . Additionally, formycin triphosphate increases atrial natriuretic factor (ANF) -stimulated guanylate cyclase activity with an EC50 of approximately 90 ?M and inhibits ATP-stimulated guanylate cyclase activity with an IC50 of around 100 ?M.
Smiles
O[C@H]1[C@H](C=2C=3C(NN2)=C(N)N=CN3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O
Molecular Formula
C10H16N5O13P3
Molecular Weight
507.18
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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