DL-threo-PPMP

CAT: 0931-T88952-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T88952-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

149022-18-4

Bioactivity

DL-threo-PPMP is an inhibitor of sphingosine synthetase (sphingosine synthetase) in Plasmodium falciparum. It inhibits the enzymes activity by binding to it, mimicking the substrate of sphingosine. This inhibition results in a rapid decline in the activity of sensitive sphingosine synthetase, selectively disrupting the interconnected tubular network in the cytoplasm of the host cell at the TVM. This action also blocks the proliferation of the Plasmodium falciparum. DL-threo-PPMP is valuable in studies of Plasmodium falciparum biology and the development of new anti-malarial strategies.

Smiles

[C@H]([C@H](O)C1=CC=CC=C1)(CN2CCOCC2)NC(CCCCCCCCCCCCCCC)=O

Molecular Formula

C29H50N2O3

Molecular Weight

474.72

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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DL-threo-PPMP

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