Molidustat sodium

CAT: 0931-T88812-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T88812-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1375799-59-9

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Chromatin/Epigenetic, Metabolism

Bioactivity

Molidustat sodium (5 μM; 20 min) is sufficient to induce detectable levels of HIF-1α in HeLa cells. In a cellular reporter assay, the compound stimulates the expression of the luciferase reporter gene under the control of a hypoxia-responsive element promoter, with an average (± SD) EC50 of 8.4 μM (n=4) .

Smiles

[Na].OC1=C(C=NN1C2=NC=NC(=C2)N3CCOCC3)N4N=NC=C4

Molecular Formula

C13H13N8NaO2

Molecular Weight

336.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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