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G9a-IN-2

CAT: 0931-T88804-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88804-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2648853-26-1
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD) .
Smiles
CC=1C2=C(NC1C(N[C@H](C(NC3=CC=C(OC4CCN(C)CC4)C=C3)=O)CCCC)=O)CC(C)(C)CC2=O
Molecular Formula
C30H42N4O4
Molecular Weight
522.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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