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E3 ligase Ligand PG

CAT: 0931-T88658-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88658-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
14149-34-9
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
E3 Ligase Ligand PG serves as an E3 ligase ligand capable of recruiting the CRBN protein. It demonstrates strong binding affinity with CRBN, exhibiting an IC50 of 2.191 μM. Furthermore, E3 Ligase Ligand PG can be linked via a linker to BMS-202 to form PROTAC, PROTACPD-L1degrader-1.
Smiles
O=C1NC(=O)C(C=2C=CC=CC2)CC1
Molecular Formula
C11H11NO2
Molecular Weight
189.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C