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IGF-1R modulator 1

CAT: 0931-T88615-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88615-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2375424-89-6
Target
EGFR, Trk receptor, IGF-1R
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), and 0.39 μM (TrkB) . This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimer's disease.
Smiles
O=C1NC(=O)N(C2=CC=C(OC=3C=CC=CC3)C(=C2)C)C(=O)N1C=4C=CC=CC4
Molecular Formula
C22H17N3O4
Molecular Weight
387.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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