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BMS-1233

CAT: 0931-T88574-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88574-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2447065-99-6
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation, Apoptosis, Cell Cycle/Checkpoint
Bioactivity
BMS-1233 is an orally effective programmed death ligand 1 (PD-L1) inhibitor with an IC50 of 14.5 nM. This compound promotes the death of HepG2 cells in a co-culture model with Jurkat T cells and exhibits antitumor activity against melanoma in mouse models.
Smiles
N#CC1=CC=CC(=C1)COC2=CC(OCC3=CC=CC(C=4C=CC=CC4)=C3C)=C(Cl)C=C2CN5CCCCC5C(=O)O
Molecular Formula
C35H33ClN2O4
Molecular Weight
581.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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