SIC-19

CAT: 0931-T88487-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T88487-01Size:25 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
713112-69-7
Target
SIK
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
SIC-19, a SIK2 inhibitor, functions by promoting the degradation of SIK2 protein via the ubiquitination pathway. It inhibits the growth of cancer cells and sensitizes cells, ovarian cancer organoids, and xenograft models to PARP inhibitors (such as Olaparib) .
Smiles
O=C(NC(=S)NNC(=O)C1=C(SC(=C1C2=CC=C(OC)C(OC)=C2)C)NC(=O)C=3C=CC=CC3)C=4C=CC=CC4
Molecular Formula
C29H26N4O5S2
Molecular Weight
574.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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Alternative Products

CatalogName
HY-163743-01SIC-19
ARC0416KU-19-19
138560-AFKeratin 19 (K19, Keratin-19, CK-19, Cytokeratin-19)
138560-AF-APCKeratin 19 (K19, Keratin-19, CK-19, Cytokeratin-19) (APC)
138560-AF-BiotinKeratin 19 (K19, Keratin-19, CK-19, Cytokeratin-19) (Biotin)
138560-AF-FITCKeratin 19 (K19, Keratin-19, CK-19, Cytokeratin-19) (FITC)
138560-AF-HRPKeratin 19 (K19, Keratin-19, CK-19, Cytokeratin-19) (HRP)
138560-AF-PEKeratin 19 (K19, Keratin-19, CK-19, Cytokeratin-19) (PE)
MBS6122291-01Keratin 19 (K19, Keratin-19, CK-19, Cytokeratin-19) (AP)
246151FLI1 (Friend Leukemia Virus Integration 1, EWSR2, SIC-1)

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