TS-IN-2

• Target:

  DNA/RNA Synthesis

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity:

  TS-IN-2 (compound 17), a potent thymidylate synthase (TS) inhibitor, exhibits an IC50 value of 0.81 ?M. It promotes apoptosis in cancer cells, induces cell cycle arrest at the S phase, and inhibits DNA synthesis, leading to DNA damage [1].

• Smiles:

  C(N1N=C(COC2=C(OC)C=C(CC=C)C=C2)OC1=S)N3CCOCC3

• Molecular Formula:

  C18H23N3O4S

• Molecular Weight:

  377.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2945983-00-4