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TS-IN-2

CAT: 0931-T87571-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87571-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2945983-00-4
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
TS-IN-2 (compound 17), a potent thymidylate synthase (TS) inhibitor, exhibits an IC50 value of 0.81 μM. It promotes apoptosis in cancer cells, induces cell cycle arrest at the S phase, and inhibits DNA synthesis, leading to DNA damage [1].
Smiles
C(N1N=C(COC2=C(OC)C=C(CC=C)C=C2)OC1=S)N3CCOCC3
Molecular Formula
C18H23N3O4S
Molecular Weight
377.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C