TS-IN-5

CAT: 0931-T204796-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T204796-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
DNA/RNA Synthesis|||Bcl-2 Family|||Apoptosis|||PI3K|||STAT
Related Pathways
Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Stem Cells|||JAK/STAT signaling|||Apoptosis|||DNA Damage/DNA Repair
Bioactivity
TS-IN-5 (Compound 15) is an inhibitor of thymidylate synthase (TS) . It induces apoptosis by modulating the proteins Bax, BCL-2, PI3K, and STAT1. TS-IN-5 exhibits antitumor activity against liver cancer, breast cancer, and colon cancer.
Smiles
CN1CCN(CC1)C2=NC=C(C(=O)N2)C3=NC4=CC=CC=C4S3
Molecular Formula
C16H17N5OS
Molecular Weight
327.404
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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