RGH-122

CAT: 0931-MF-0121277-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0121277-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2355304-05-9
Target
Vasopressin Receptor
Related Pathways
GPCR/G Protein
Bioactivity
RGH-122 (compound 43), characterized as an orally active, potent, and selective hV1a receptor antagonist, demonstrates significant affinity with a K i value of 0.3 nM and an IC 50 of 0.9 nM. It exhibits microsomal stability, indicated by a CL int value of 13/28/25 ?L/min/mg [1].
Smiles
ClC=1C=C2CC3(CC=4N(C2=CC1)C(=NN4)[C@@H]5CC[C@@H](OC6=CC=CC=N6)CC5)OCCO3
Molecular Formula
C24H25ClN4O3
Molecular Weight
452.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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