RGH-122

• CAS Number :

  2355304-05-9

• Target :

  Vasopressin Receptor

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  RGH-122 (compound 43), characterized as an orally active, potent, and selective hV1a receptor antagonist, demonstrates significant affinity with a K i value of 0.3 nM and an IC 50 of 0.9 nM. It exhibits microsomal stability, indicated by a CL int value of 13/28/25 ?L/min/mg [1].

• Smiles :

  ClC=1C=C2CC3(CC=4N(C2=CC1)C(=NN4)[C@@H]5CC[C@@H](OC6=CC=CC=N6)CC5)OCCO3

• Molecular Formula :

  C24H25ClN4O3

• Molecular Weight :

  452.93

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C