PERK/eIF2? activator 1

• Target:

  PERK

• Related Pathways:

  Apoptosis

• Bioactivity:

  Compound V8 (PERK/eIF2? activator 1), a flavonoid, exhibits anti-tumor properties by inducing apoptosis and activating the PERK-eIF2?-ATF4 pathway. It effectively inhibits the proliferation of HepG2 cells, with an IC 50 value of 23 ?M [1].

• Smiles:

  O(C)C1=C2C(C(=O)C=C(O2)C3=CC=CC=C3)=C(O)C=C1OCCCCN(CCO)CCO

• Molecular Formula:

  C24H29NO7

• Molecular Weight:

  443.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1178583-17-9