PERK/eIF2? activator 1

• Target :

  PERK

• Related Pathways :

  Apoptosis

• Bioactivity :

  Compound V8 (PERK/eIF2? activator 1), a flavonoid, exhibits anti-tumor properties by inducing apoptosis and activating the PERK-eIF2?-ATF4 pathway. It effectively inhibits the proliferation of HepG2 cells, with an IC 50 value of 23 ?M [1].

• Smiles :

  O(C)C1=C2C(C(=O)C=C(O2)C3=CC=CC=C3)=C(O)C=C1OCCCCN(CCO)CCO

• Molecular Formula :

  C24H29NO7

• Molecular Weight :

  443.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1178583-17-9