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Myosin-IN-1

CAT: 0931-T86938-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86938-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
849011-39-8
Target
Myosin
Related Pathways
Cytoskeletal Signaling
Bioactivity
Myosin-IN-1 (compound F10), a specific inhibitor of cardiac myosin, acts by stabilizing the cardiac myosin motor domain in its closed biochemical and structural state. It reduces myocardial force production and calcium sensitivity, functioning as a negative inotropic agent. In isolated Langendorff-perfused rat hearts, Myosin-IN-1 decreases stress in myofilaments and diminishes the development of left ventricular pressure. This compound is applicable in heart failure research [1].
Smiles
O=C1C2=C(SC(CC)=C2)N=CN1NC(NC(C)C)=S
Molecular Formula
C12H16N4OS2
Molecular Weight
296.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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