JAK1-IN-12

CAT: 0931-T86756-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T86756-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2945204-95-3

Target

JAK

Related Pathways

Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic, JAK/STAT signaling, Angiogenesis

Bioactivity

JAK1-IN-12, a selective inhibitor of JAK1, exhibits an IC50 of 0.0246 μM and demonstrates IC50 values of 0.423 μM, 0.410 μM, and 1.12 μM for JAK2, JAK3, and TYK2, respectively. It promotes hair growth in mice and is applicable for researching immune and inflammatory diseases [1].

Smiles

N([C@@H]1[C@@]2(CC3(O)C[C@@]1(CC(C2)C3)[H])[H])C=4C(=CN=C5C4C=CN5)C=6C=NNC6

Molecular Formula

C20H23N5O

Molecular Weight

349.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-149296	JAK1-IN-12
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