HWY-289

• Target:

  Antifungal

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  HWY-289, a semisynthetic protoberberine derivative, exhibits broad-spectrum and potent activities against phytopathogenic fungi, especially Botrytis cinerea (EC 50 = 1.34 ?g/mL) . It alters the morphology of the mycelium and the internal structure of cells while decreasing ATP content, ATPase activities, and key enzyme activities in the TCA cycle [1].

• Smiles:

  C(C1=C2C=3C(=CC4=C(C3)OCO4)CC[N+]2=CC=5C1=CC=C(OC)C5OC)C6=CC=C(C(C)(C)C)C=C6.[Br-]

• Molecular Formula:

  C31H32BrNO4

• Molecular Weight:

  562.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  908001-51-4