SR-2890

• Target :

  Casein Kinase

• Related Pathways :

  Stem Cells|||Metabolism

• Purity :

  0.991

• Bioactivity :

  SR-2890 is a potent and highly selective casein kinase 1?/1? (CK1?/?) inhibitor with an IC50 of 4 nM for CK1?. This compound inhibits melanoma A375 cell growth with an EC50 of 38 nM in MTT assays and possesses pharmacokinetic properties suitable for xenograft studies using human cancer cell lines.

• Smiles :

  FC1=CC=CC(=C1)N2C=NC=3C(=NC(=NC32)N4CCNCC4)NCC5=NC=6C=CC(Cl)=CC6N5

• Molecular Formula :

  C23H21ClFN9

• Molecular Weight :

  477.93

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1454584-91-8