Products for Research Use Only

HSD17B13-IN-42

CAT: 0931-T86632-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T86632-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2770246-10-9
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-42 (compound 10) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with an IC50 of < 0.1 μM using estradiol as substrates. HSD17B13-IN-42 plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=CC(OC(F)(F)F)=CC=C4)C3=O)=CC=C2
Molecular Formula
C23H14Cl2F3N3O4
Molecular Weight
524.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Popular Products