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HSD17B13-IN-16

CAT: 0931-T86606-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86606-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2758802-09-2
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-16 (compound 8) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of <0.1 μM and <1 μM when using estradiol and Leukotriene B3 as substrates, respectively. The compound is notably significant in the treatment of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
C(NCC1=C(OC)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(Cl)=C(O)C=C3)C=CS2
Molecular Formula
C20H17ClN2O4S
Molecular Weight
416.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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