FL77-24

CAT: 0931-T86429-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T86429-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2413582-39-3

Target

Apoptosis

Related Pathways

Apoptosis

Bioactivity

FL77-24, an analog of FL118 and an apoptosis inducer, exhibits antitumor activity with IC50 values of 99.4 nM in HCT116 cells, 118 nM in HepG2 cells, less than 6.4 nM in both MCF-7 and HeLa cells, and 28.5 nM in A549 cells. It primarily induces cell cycle arrest in the S and G2/M phases [1].

Smiles

O(C)C=1C=C(C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=CC7=C(C6)OCO7)C=C(OC)C1

Molecular Formula

C29H24N2O8

Molecular Weight

528.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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FL77-24

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