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Emavusertib hydrochloride

CAT: 0931-T86366-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T86366-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2376399-42-5
Target
NF-κB, MyD88, IRAK, Apoptosis, FLT
Related Pathways
Immunology/Inflammation, Angiogenesis, NF-κB, Tyrosine Kinase/Adaptors, Apoptosis
Bioactivity
Emavusertib (CA-4948) hydrochloride, a selective and potent IRAK4/FLT3 inhibitor, is designed for oral administration. It achieves an IC 50 of 57 nM against IRAK4 in a FRET kinase assay and demonstrates anti-tumor activity [1] [2] [3].
Smiles
N(C(=O)C=1N=C(OC1)C=2C=C(C)N=CC2)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CC[C@@H](O)C6.Cl
Molecular Formula
C24H26ClN7O5
Molecular Weight
527.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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