Products for Research Use Only

DAPM

CAT: 0931-T86161-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T86161-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
208255-51-0
Target
Gamma-secretase
Related Pathways
Stem Cells, Proteases/Proteasome, Neuroscience
Purity
0.9976
Bioactivity
DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects, inhibits cell proliferation and induces the expression of Krüppel-like Factor 4 (KLF4) and p21 in human colon cancer cells, inhibits Notch signaling, and can be used in the study of renal tubular adenomas.
Smiles
[C@@H](NC([C@@H](NC(CC1=CC(F)=CC(F)=C1)=O)C)=O)(C(OC)=O)C2=CC=CC=C2
Molecular Formula
C20H20F2N2O4
Molecular Weight
390.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C