BAY-155

• CAS Number :

  2163769-52-4

• Target :

  Epigenetic Reader Domain

• Related Pathways :

  Chromatin/Epigenetic

• Bioactivity :

  BAY-155 is a powerful and selective menin-MLL inhibitor, exhibiting an IC 50 of 8 nM. It significantly down-regulates MEIS1 gene expression while up-regulating CD11b and MNDA genes. BAY-155 also demonstrates anti-proliferative effects in AML/ALL (acute myeloid/lymphoblastic leukemia) models [1].

• Smiles :

  N#CC1=CC=2C(=CC=C(C2C)CN3CCC4(CN(C=5N=CN=C6SC(=CC65)CC(F)(F)F)C4)CC3)N1CC(=O)N

• Molecular Formula :

  C28H28F3N7OS

• Molecular Weight :

  567.63

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C