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BAY-155

CAT: 0931-T85802-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T85802-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2163769-52-4
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
BAY-155 is a powerful and selective menin-MLL inhibitor, exhibiting an IC 50 of 8 nM. It significantly down-regulates MEIS1 gene expression while up-regulating CD11b and MNDA genes. BAY-155 also demonstrates anti-proliferative effects in AML/ALL (acute myeloid/lymphoblastic leukemia) models [1].
Smiles
N#CC1=CC=2C(=CC=C(C2C)CN3CCC4(CN(C=5N=CN=C6SC(=CC65)CC(F)(F)F)C4)CC3)N1CC(=O)N
Molecular Formula
C28H28F3N7OS
Molecular Weight
567.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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