RegisterLogin

BAY 593

CAT: 0931-T201377-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T201377-01Size:100 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2413020-57-0
Target
YAP
Related Pathways
Stem Cells
Bioactivity
BAY 593 functions as an inhibitor of geranylgeranyltransferase-I (GGTase-I), effectively preventing the activation of Rho-GTPases and consequently inactivating YAP1/TAZ signaling pathways. It has been shown to inhibit tumor growth dose-dependently in xenograft mouse models, exhibiting IC50 values of 38.4 nM in MT-1080 cells and 564 nM in MDA-MB-231 cells, as well as in PXF 541 xenografts.
Smiles
O(C)C1=C([C@H]2C3(CCN(C([C@](C(F)(F)F)(OC)C4=CC=CC=C4)=O)CC3)CCNC2)C=CC=C1.Cl
Molecular Formula
C26H32ClF3N2O3
Molecular Weight
512.99
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T16975-01TAK-593
T73053-01BAY 2965501
T69689-01BAY-693
T70133-01BAY-846
TYD-02414-01(±) -BAY-7081
T88844-01BAY 2925976
T30302-01BAY-751098
T10469-01BAY-298
T5208-01BAY-8002
T9805-01BAY 2666605

Alternative Products

CatalogName
APPDE 300Plasmid DNA Extraction Mini Kit (300prep) (sample size:1~3 ml culture)
APGCK 050GEL/PCR Purification Mini Kit (50prep)
APPCK 200PCR Clean-Up Mini Kit (200prep)
APGPK 200GEL Purification Mini Kit (200prep)
APPGK 100Plant Genomic DNA Extraction Mini Kit (100prep)
APGDC 050FavorPrep Genomic DNA Clean-Up Kit (50prep)
APGDC 200FavorPrep Genomic DNA Clean-Up Kit (200prep)
APVNK 200Viral Nucleic Acid Extraction Kit (200prep), (With Carrier RNA, for low viral load specimen using carrier RNA)
APEBD 002-3Alphagen EtBr Destroyer Sprayer
APRND 001-1Alphagen RNase Destroyer Sprayer

Popular Products